2-chloroethyl methyl ether

• Category :

  Intermediates/Pharmaceutical intermediates

• Synonyms :

  1-chloro-2-methoxyethane;2-Methoxyethyl chloride;

• CAS NO :

  627-42-9

• EC NO :

  210-999-7

• Molecular Formula :

  C₃H₇ClO

• Molecular Weight :

  94.54

• Main Specifications :

  99% min

• InChI :

  InChI=1/C3H7ClO/c1-5-3-2-4/h2-3H2,1H3

• Packing :

  25kg，50kg 200kg

• Product description :

  What is the chemical of 2-chloroethyl methyl ether? Appearance: Colorless to pale yellow transparent oily liquid ; Assay：99%min by GC ; IR Identity: conform to standard ; HNMR： conform to standard ; carbon spectrum: conform to standard ; Water by K. F.:0.5% max or as per the customer’s request ; Loss on drying:0.5% max. or as per the customer’s request ; Melting point: -55 °C ; boiling point: 89–90 °C; ============================================================================== Purpose: Mainly used as pharmaceutical intermediates and pesticide intermediates Used for synthesizing various drugs and pesticide compounds As an important intermediate in organic synthesis ============================================================================= synthetic route According to publicly available information, the typical synthesis method of 2-chloroethyl methyl ether is as follows Raw materials: 2-chloroethanol+dimethyl sulfate Catalyst/deacidification agent: calcium carbonate (CaCO ∝) Reaction conditions: Heat to 120-130 ° C Reaction time: Approximately overnight (until distillation stops) Post processing: Dilute the distillate with ether Wash with 2N NaOH solution to remove acidic impurities Extract the water layer with ether again Combine ether layers and dry with anhydrous MgSO ? Purification: Distillation, collect 88-90 ° C fractions Yield: Approximately 43% (based on 2-chloroethanol)

• Uses :

  Mainly used as pharmaceutical intermediates and pesticide intermediates

• Molecular Structure :