HPMC

• Category :

  Organic chemicals and Derivatives

• Synonyms :

  HPMC;(2R,3R,4S,5R,6S)-3,4,5-trimethoxy-2-(methoxymethyl)-6-[(2R,3R,4S,5R,6R)-4,5,6-trimethoxy-2-(methoxymethyl)tetrahydropyran-3-yl]oxy-tetrahydropyran;1-[[(2R,3R,4S,5R,6S)-3,4,5-tris(2-hydroxypropoxy)-6-[(2R,3R,4S,5R,6R)-4,5,6-tris(2-hydroxypropoxy)-2-(2-hydroxypropoxymethyl)tetrahydropyran-3-yl]oxy-tetrahydropyran-2-yl]methoxy]propan-2-ol;Hydroxypropyl methylcellulose;Hydroxypropyl methyl cellulose;HPMCP-HP55;

• CAS NO :

  9004-65-3

• EC NO :

• Molecular Formula :

  C₁₂H₂₀O₁₀

• Molecular Weight :

  324.2848

• Main Specifications :

• InChI :

  InChI=1/C36H70O19.C20H38O11/c1-19(37)9-45-17-27-29(47-11-21(3)39)31(48-12-22(4)40)34(51-15-25(7)43)36(54-27)55-30-28(18-46-10-20(2)38)53-35(52-16-26(8)44)33(50-14-24(6)42)32(30)49-13-23(5)41;1-21-9-11-13(23-3)15(24-4)18(27-7)20(30-11)31-14-12(10-22-2)29-19(28-8)17(26-6)16(14)25-5/h19-44H,9-18H2,1-8H3;11-20H,9-10H2,1-8H3/t19?,20?,21?,22?,23?,24?,25?,26?,27-,28-,29-,30-,31+,32+,33-,34-,35-,36+;11-,12-,13-,14-,15+,16+,17-,18-,19-,20+/m11/s1

• Product description :

  1.Chemical name:HYDROXYPROPYLMETHYL CELLULOSE(MHPC).

  2.Specification:

  Index	Type
  	ME	MF	MK
  Methoxyl content(WT%)	28.0-30.0	27.0-30.0	19.0-24.0
  Hydroxypropoxyl content(WT%)	7.0-12.0	4.0-7.5	4.0-12.0
  Gelation temperature(ºC)	58.0-64.0	62.0-68.0	70.0-90.0
  PH value(1% solution ,25oC)	4.0-8.0
  Ash content(WT%)	≤ 0.5 (1.0-Industry grade)
  Loss on drying (WT%)	≤ 5.0
  Burnt residues(WT%)-pharm grade	≤ 1.5
  Heavy metal(PPM)-pharm grade	≤ 20
  Arsenic(PPM)-pharm grade	≤ 2
  Viscosity,(mpas)	5-150000

  3.Properties:

  Appearance:White powder.
  Particle size:98.0%min through 100mesh.
  Charring temperature:280-300 Deg.C.
  Bulk density:0.25-0.70g/cm³(Usually around 0.5g/cm³)
  Real specific gravity:1.26-1.31
  Browning temperature:190-200 Deg.C.
  Surface tension(2% water solution):42-56 dyn/cm.
  It can be dissolved in water and some organic solvent such as ethanol,propyl alcohol,ethylene chloride,the water solution is of surface activity,It is a nonionic surface active agent,Gelation temperature is different for different grades.

  4.Applications:

      Chemical ingredient HPMC are widely used in food ,cosmetic and other daily use chemical lines, Typical usage as following:
  A. Industry grade
       Used as construction material such as plaster,renders,mortars,tile adhesives,fillers,emulsion paints.or used for PVC polymerization,

  B. Medical drug.
  The product is a medical accessory material of may uses. It can be used for densifiers, dispersing reagent, emulsifying reagent, Lubricator and former etc, It's used as an adhesive and coating film in tablets, increasing markedly rate of dissolution and release,and strengthen water proof for tablets and also be used as mixed dispersing reagent ,eye drop reagent,controlled released matrix tablets,It is combined with other synthetic polymers and gel-type drug products to prevent ethanol separated from transparent gel drug while improve water keep ability.
  C.Foodstuff.
  HPMC can be directly used to food as effective emulsification  reagent , adhesive, thickening reagent as well as can be used as packing materials.
  D. Cosmetic.
  According to properties of HPMC, it can be used as thickening agent, emulsification reagent, suspending reagent, stabilizing reagent, water retention reagent, rheological  behavior reagent, Thus be used in all kinds of cosmetic products.

  5.Packing, storage, transportation:

  20kg or 25kg package in PP bag or drums with inner liners, Keep dry where good ventilated ,Do not wet ,and keep from sunshine when transport.

• Molecular Structure :