2-chloroethyl methyl ether
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- Category :
Intermediates/Pharmaceutical intermediates
- CAS NO : 627-42-9
- EC NO : 210-999-7
- Molecular Formula : C3H7ClO
- Main Specifications : 99% min
- Synonyms : 1-chloro-2-methoxyethane;2-Methoxyethyl chloride;
Package: 25kg，50kg 200kg
Uses : Mainly used as pharmaceutical intermediates and pesticide intermediates
Molecular Structure:
Product description:
What is the chemical of 2-chloroethyl methyl ether?
Appearance: Colorless to pale yellow transparent oily liquid ;
Assay：99%min by GC ;
IR Identity: conform to standard ;
HNMR： conform to standard ;
carbon spectrum: conform to standard ;
Water by K. F.:0.5% max or as per the customer’s request ;
Loss on drying:0.5% max. or as per the customer’s request ;
Melting point: -55 °C ;
boiling point: 89–90 °C;
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Purpose:
Mainly used as pharmaceutical intermediates and pesticide intermediates
Used for synthesizing various drugs and pesticide compounds
As an important intermediate in organic synthesis
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synthetic route
According to publicly available information, the typical synthesis method of 2-chloroethyl methyl ether is as follows
Raw materials: 2-chloroethanol+dimethyl sulfate
Catalyst/deacidification agent: calcium carbonate (CaCO ∝)
Reaction conditions:
Heat to 120-130 ° C
Reaction time: Approximately overnight (until distillation stops)
Post processing:
Dilute the distillate with ether
Wash with 2N NaOH solution to remove acidic impurities
Extract the water layer with ether again
Combine ether layers and dry with anhydrous MgSO ?
Purification: Distillation, collect 88-90 ° C fractions
Yield: Approximately 43% (based on 2-chloroethanol)
If you are sourcing 2-chloroethyl methyl ether from China ,just feel free to inquire
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